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Degradation of motor neurons, conceptual computer illustration. Motor neuron diseases are a group of neurodegenerative disorders including amyotrophic lateral sclerosis, progressive bulbar palsy and other. Amyotrophic lateral sclerosis, also referred to as Lou Gehrig's disease is the most common of the motor neuron diseases. Nerve degeneration and restricted production of the neurotransmitter dopamine results in deterioration of muscle tissue. This debilitating disease is characterized by rapidly progressive weakness, muscle atrophy and twitching, muscle spasticity, difficulty speaking (dysarthria), difficulty swallowing (dysphagia), and difficulty breathing (dyspnea).
Blog Post

Simply Stated: Updates in Neuromuscular Junction (NMJ) Disorders

By Sujatha Gurunathan | March 31, 2025
Brunette woman working out on wheelchair at home.
Blog Post

Pro Tips to Add More Movement to Your Day

By Rebecca Hume | March 28, 2025
Barbara and Jim Twardowski pose on a bridge over the Seine in Paris with the Eiffel Tower visible in the background. Barbara is sitting in a wheelchair and Jim is standing behind her.
Blog Post

Essential Gear for Traveling with a Disability

By Barbara and Jim Twardowski, RN | March 24, 2025
Blog Post

Insights by Ira: A Celebration of the Best of MDA Center Care Physicians

By Ira Walker | March 20, 2025
Blog Post

Making an Impact on Day 1 of the MDA Clinical and Scientific Conference

By Amy Bernstein | March 18, 2025
Blog Post

Celebrating 25 Years of Impact: MDA’s Wings Over Wall Street Gala Honors Leaders in ALS Research and Advocacy

By MDA Staff | March 16, 2025
at burn with family in workout clothes: from left to right: Bryce Pattison (boyfriend), Ann Lopiccolo (mom-burn ambassador), Grace LoPiccolo (me), Molly Graf (sister), Stephen Graf (brother-in-law- trainer)
Blog Post

MDA Ambassador Guest Blog: Make Sense? Say Yes!

By Grace LoPiccolo | March 13, 2025
Vector drawing of young woman with an electric wheelchair walking outside the city with her friends.
Blog Post

Five Tips to Increase Socialization this Spring

By Rebecca Hume | March 11, 2025
wooden blocks spell out the word content with word bubbles above that say news and stories and photos and blog
Blog Post

In Case You Missed It…

By MDA Staff | March 8, 2025
Blog Post

Quest Podcast: PJ’s Protocol: A Lifesaving Procedure Fueled by Love

By MDA Staff | March 6, 2025
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