Clinical Research Opportunity: LION-CS101 a Phase 1/2 Study of AB-1003 in Adults with LGMD2I/R9

Researchers at AskBio are seeking adults with genetically confirmed limb-girdle muscular dystrophy (LGMD) type 2I/R9 to participate in a phase 1/2 clinical trial (LION-CS101) to evaluate the safety and tolerability of the investigational gene therapy AB-1003 to treat LGMD2I/R9. LGMD2I/R9 is a rare form of LGMD caused by changes in the FKRP gene and is associated…

Simply Stated: Updates in Neuromuscular Junction (NMJ) Disorders

The neuromuscular junction (NMJ) disorders are a group of conditions that disrupt the communication between motor neurons and muscles, resulting in muscle weakness, fatigue, problems with movement and mobility, and, in severe cases, paralysis. Recognized NMJ disorders include the autoimmune disorders myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS), the genetic conditions known as congenital myasthenic…

Pro Tips to Add More Movement to Your Day

Adding more movement or physical activity to each day is a common goal among people living with neuromuscular disease. However, muscle fatigue, weakness, and limited strength or range of motion can make increasing physical activity a challenge. The age-old conundrum of “if you don’t use it, you lose it” conflicts with the need for rest…

Essential Gear for Traveling with a Disability

Discover essential gear to pack for a smooth trip when traveling with a disability, from mobility aids to adaptive equipment.

Insights by Ira: A Celebration of the Best of MDA Center Care Physicians

Prior to the start of 2025, I began the usual and customary exercise of establishing professional and personal goals for the new year.  While I have many goals this year, including writing my first fiction novel, expanding my culinary abilities and sharing my love of cooking through online videos, and continuing to have a consistent…

Making an Impact on Day 1 of the MDA Clinical and Scientific Conference

The first day of the 2025 MDA Clinical & Scientific Conference featured stirring opening remarks, research awards, and a keynote by the former FDA Commissioner.

Celebrating 25 Years of Impact: MDA’s Wings Over Wall Street Gala Honors Leaders in ALS Research and Advocacy

For a quarter of a century, MDA’s Wings Over Wall Street has brought the ALS community together in New York City, raising millions of dollars to advance research and improve care. This year marks the 25th anniversary of the annual benefit, an evening dedicated to honoring extraordinary individuals who are driving progress in the fight…

MDA Ambassador Guest Blog: Make Sense? Say Yes!

Grace LoPiccolo, 21, of St. Louis, Missouri, was diagnosed with CMT-1A at the age of nine. She currently attends Saint Louis University majoring in Bioethics and Health Studies, and  Catholic studies. She is currently a Junior but ultimately plans on attending law school and pursuing a field in health and disability policy. Additionally, at Saint…

Five Tips to Increase Socialization this Spring

Increasing socialization, cultivating meaningful relationships and friendships, and limiting isolation or loneliness in an increasingly remote world is a desire – and challenge – for many adults. Individuals living with disabilities sometimes face additional barriers of physical accessibility and social inclusion in their pursuit of a healthy and fulfilling social life. Add to that a…

In Case You Missed It…

Quest Media is an innovative adaptive lifestyle platform from MDA. With the power of this platform, we foster awareness and empowerment and have important conversations with experts, thought leaders, and members of the neuromuscular disease community about topics that matter to them and to the larger community of individuals with disabilities. With so many valuable…

Quest Media is an innovative adaptive lifestyle platform from MDA. With the power of this platform, we foster awareness and empowerment and have important conversations with experts, thought leaders, and members of the neuromuscular disease community about topics that matter to them and to the larger community of individuals with disabilities. 

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Clinical Research Opportunity: LION-CS101 a Phase 1/2 Study of AB-1003 in Adults with LGMD2I/R9

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QUEST PODCAST

The Quest podcast, proudly presented by the Muscular Dystrophy Association, is part of the Quest family of content. Hosted by Quest Editor-in-Chief, motivational speaker and writer Mindy Henderson.

See All Episodes

Episode 50- PJ’s Protocol: A Lifesaving Procedure Fueled by Love

March 6, 2025

In this episode of Quest Podcast, we chat with three pillars of the Duchenne muscular dystrophy community who are here with us on the 10th anniversary of PJ’s protocol. First, we have Brian Nicholoff whose son’s untimely passing was the catalyst for the creation of PJ’s protocol. Next is Amy Aikens whose son’s life was…

Episode 49- Navigating Romance with MDA Ambassadors

February 13, 2025

In this episode of Quest Podcast, we chat with three of our MDA Ambassadors. Nora is a passionate animal advocate and lives with Selenon (SEPN1)-related myopathy (RM). Justin is a disability advocate and an Operations Manager and lives with Limb-girdle Muscular Dystrophy and K.L. is an entrepreneur, poker professional, and influencer living with Spinal Muscular…

Episode 48- Living with Intention and Creating a More Beautiful Life

January 28, 2025

In this Quest Podcast episode, we chat with a certified Life Coach who lives with spinal muscular atrophy. Amber Bosselman has devoted her career to providing living skills for individuals with physical disabilities and helping them find personal fulfillment and develop strategies to improve their lives and reach their goals. Amber joins us to share…