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Blog Post | News, Science + Research

Biogen Releases Letter to ALS Community

Yesterday, Biogen released a letter to the ALS community regarding its experimental therapy, tofersen (formerly known as BIIB067), an antisense oligonucleotide being studied for the potential treatment of amyotrophic lateral…

Tags: Antisense Oligonucleotide, Clinical Trials, Drug Development, Research, Research Advances


Blog Post | News, Science + Research

Mouse Study Finds Link Between Key Mitochondrial Protein and CMT2A, Making It a Possible Therapeutic Target

In a study conducted in mice, scientists led by an MDA-funded researcher found that increasing the amount of a certain mitochondrial membrane protein, mitofusin-1 (MFN1), lessened symptoms of Charcot-Marie-Tooth disease…

Tags: Gene Therapy, Grants, Research


Blog Post | News, Science + Research

Clinical Trial Alert: PTC Therapeutics Seeks Participants for a Phase 3 DMD Study

Researchers at PTC Therapeutics are looking for participants with Duchenne muscular dystrophy (DMD) to participate in a Phase 3 study. The goal of the study is to characterize the long-term…

Tags: Clinical Trial Alert, Clinical Trials, Drug Development, Research


Blog Post | Personal Stories

Introducing New MDA National Ambassador Tana Zwart, and Checking in With Ambassadors Faith Fortenberry and Justin Moy

Since the early 1950s, not long after the Muscular Dystrophy Association’s formation, America’s young people living with muscular dystrophy and related neuromuscular diseases have stepped forward to share their stories,…

Tags: Ambassadors, Community, Summer Camp, Young Adults


Blog Post | News, Science + Research

MDA Partners with the Broad Institute on Rare Genomes Project for Limb-Girdle Muscular Dystrophy

The Muscular Dystrophy Association (MDA) is pleased to announce a collaboration with the Broad Institute of MIT and Harvard, which aims to bring genetic diagnoses to more individuals living with…

Tags: Genetic Testing, Grants, Research


Blog Post | News, Science + Research

Muscular Dystrophy Association Bridges Clinical and Academic Neuromuscular Research for the First Time at Annual Meeting

With a laser focus on new horizons in neuromuscular research and care, the Muscular Dystrophy Association (MDA) is combining its clinical and scientific conferences for the first time, establishing a…

Tags: Gene Therapy, MDA Clinical and Scientific Conference, Newborn Screening, Research, Technology


Blog Post | News, Science + Research

Audentes Therapeutics Announces Plans to Develop Gene-Targeted Therapies for Duchenne Muscular Dystrophy and Myotonic Dystrophy Type 1

On April 8, Audentes Therapeutics announced that it will expand its gene-targeted therapy platform to include developing experimental drugs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1).…

Tags: Antisense Oligonucleotide, Drug Development, Exon Skipping, Gene Therapy, Research


Blog Post | Personal Stories

A Tale of Two Siblings: Twin MDA Volunteers Forge Lifelong Connections — and Careers

Twin brother and sister Michael and Amy Schleicher’s story starts where a lot of kids’ stories do. They looked up to their big brother, Matt, and when he did something…

Tags: Community, MDA Care Centers, Muscle Walk, Summer Camp, Volunteers


Blog Post | News, Science + Research

Muscular Dystrophy Association Awards Eight Grants Totaling More Than $2 Million for ALS Research

Today, the Muscular Dystrophy Association (MDA) announced the awarding of eight new grants totaling more than $2 million toward research focused on amyotrophic lateral sclerosis (ALS), a disease in which…

Tags: Antisense Oligonucleotide, Drug Development, Gene Therapy, Grants, Research


Blog Post | News, Science + Research

Sarepta Therapeutics Announces Positive Interim Results from Study of Casimersen to Treat DMD Amenable to Exon 45 Skipping

On Mar. 28, Sarepta Therapeutics announced encouraging interim results from a phase 3 clinical trial that suggest the experimental drug casimersen potentially may be effective as a treatment for Duchenne muscular…

Tags: Clinical Trials, Drug Development, Exon Skipping, Gene Therapy